A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis
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Chooi, Yit-Heng
Hong, Young J
Cacho, Ralph A
Tantillo, Dean J
Tang, Yi
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American Chemical Society
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Viridicatumtoxin (1) is a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system. Puzzlingly, no dedicated terpene cyclase is found in the gene cluster identified in Penicillium aethiopicum. Cytochrome P450 enzymes VrtE and
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Journal of the American Chemical Society
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2037-12-31
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