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Interferon-gamma as a Possible Target in Chronic Asthma

Date

Authors

Kumar, Rakesh K

Webb, Dianne

Herbert, Cristan

Foster, Paul S

Publisher

Bentham Science Publishers Ltd

Abstract

The role of interferon-γ (IFN-γ) in asthma is controversial. However, this cytokine has been proposed to play a role both acute severe asthma and chronic stable asthma. We have shown that in a chronic low-level challenge model of allergic asthma in mice

Keywords

Keywords: gamma interferon; gamma interferon antibody; interleukin 5 antibody; article; asthma; bronchus hyperreactivity; CD4+ T lymphocyte; CD8+ T lymphocyte; clinical feature; cytokine production; disease course; disease exacerbation; disease severity; down regul Acute exacerbation; Airway hyper-reactivity; Asthma; Interferon-?; Th1 and Th2 cytokines

URI

http://hdl.handle.net/1885/22309

Collections

ANU Research Publications

Source

Inflammation and Allergy - Drug Targets

Type

Journal article

DOI

10.2174/187152806779010909