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Requirement of dendretic calcium spikes for induction of spike-timing-dependent synaptic plasticity

Date

Authors

Kampa, Bjoern

Letzkus, Johannes

Stuart, Gregory J

Publisher

Cambridge University Press

Abstract

Spike-timing-dependent synaptic plasticity (STDP) by definition requires the temporal association of pre- and postsynaptic action potentials (APs). Yet, in cortical pyramidal neurons pairing unitary EPSPs with single APs at low frequencies is ineffective

Keywords

Keywords: calcium channel blocking agent; calcium channel R type; calcium channel T type; n methyl dextro aspartic acid receptor; nickel; animal cell; apical meristem; article; calcium signaling; concentration response; controlled study; dendrite; excitatory postsy

URI

http://hdl.handle.net/1885/17694

Collections

ANU Research Publications

Source

Journal of Physiology

Type

Journal article

DOI

10.1113/jphysiol.2006.111062

Restricted until

2037-12-31

Downloads

File

Description

01_Kampa_Requirement_of_dendretic_2006.pdf (381.46 KB)