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Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis

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Authors

Jackson, Colin J
Taylor, Matthew C
Tattersall, David B
French, Nigel G
Carr, Paul D
Ollis, David
Russell, Robyn
Oakeshott, John Graham

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Blackwell Publishing Ltd

Abstract

Pyridoxine 5′-phosphate oxidases (PNPOxs) are known to catalyse the terminal step in pyridoxal 5′-phosphate biosynthesis in a flavin mononucleotide-dependent manner in humans and Escherichia coli. Recent reports of a putative PNPOx from Mycobacterium

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Acta Crystallographica Section F: Structural Biology and Crystallization Communications

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2037-12-31