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The HP1-p150/CAF-1 interaction is requried for pericentric heterochromatin replication and S-phase prgoression in mouse cells

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Authors

Quivy, Jean-Pierre
Gerard, Annabelle
Cook, Adam
Roche, Daniele
Almouzni, Genevieve

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Nature Publishing Group

Abstract

The heterochromatin protein 1 (HP1)-rich heterochromatin domains next to centromeres are crucial for chromosome segregation during mitosis. This mitotic function requires their faithful reproduction during the preceding S phase, a process whose mechanism

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Nature Structural and Molecular Biology

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Restricted until

2037-12-31
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