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L-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablasts

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Date

2013

Authors

Berglund, Lucinda J.
Avery, Danielle T
Ma, Cindy
Moens, Leen
Deenick, Elissa
Bustamante, Jacinta
Wong, Melanie
Adelstein, Stephen
Arkwright, Peter D
Bacchetta, Rosa

Journal Title

Journal ISSN

Volume Title

Publisher

American Society of Hematology

Abstract

B-cell responses are guided by the integration of signals through the B-cell receptor (BCR), CD40, and cytokine receptors. The common γ chain (γc)-binding cytokine interleukin (IL)-21 drives humoral immune responses via STAT3-dependent induction of tran

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/53912

Collections

ANU Research Publications

Source

Blood

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1182/blood-2013-06-506865

Restricted until

2037-12-31

Downloads

File
Description
01_Berglund_L-21_signalling_via_STAT3_2013.pdf (1.7 MB)

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