Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis
| dc.contributor.author | Mullbacher, Arno | |
| dc.contributor.author | Lobigs, Mario | |
| dc.contributor.author | Tha Hla, Ron | |
| dc.contributor.author | Tran, Thao (Thomas) | |
| dc.contributor.author | Stehle, Thomas | |
| dc.contributor.author | Simon, Markus M | |
| dc.date.accessioned | 2015-12-13T22:24:54Z | |
| dc.date.issued | 2002 | |
| dc.date.updated | 2015-12-11T08:11:31Z | |
| dc.description.abstract | Effector cytolytic T (Tc) lymphocytes, deficient in the exocytosis-mediated pathway of target cell lysis, induce Fas on target cells and, in turn, delayed cell death and apoptosis via the Fas ligand-Fas interaction. The induction of Fas can be blocked by | |
| dc.identifier.issn | 0022-1767 | |
| dc.identifier.uri | http://hdl.handle.net/1885/72973 | |
| dc.publisher | American Association of Immunologists | |
| dc.source | Journal of Immunology | |
| dc.subject | Keywords: antibody; Fas antigen; FAS ligand; major histocompatibility antigen; recombinant gamma interferon; T lymphocyte receptor; animal cell; apoptosis; article; bystander effect; cell death; cytolysis; cytotoxic T lymphocyte; effector cell; exocytosis; knockout | |
| dc.title | Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis | |
| dc.type | Journal article | |
| local.bibliographicCitation.lastpage | 150 | |
| local.bibliographicCitation.startpage | 145 | |
| local.contributor.affiliation | Mullbacher, Arno, College of Medicine, Biology and Environment, ANU | |
| local.contributor.affiliation | Lobigs, Mario, College of Medicine, Biology and Environment, ANU | |
| local.contributor.affiliation | Tha Hla, Ron, College of Medicine, Biology and Environment, ANU | |
| local.contributor.affiliation | Tran, Thao (Thomas), Victorian Infectious Diseases Reference Laboratory | |
| local.contributor.affiliation | Stehle, Thomas, Max Planck Institute of Immunobiology | |
| local.contributor.affiliation | Simon, Markus M, Max Planck Institute of Immunobiology | |
| local.contributor.authoruid | Mullbacher, Arno, u8102295 | |
| local.contributor.authoruid | Lobigs, Mario, u8506091 | |
| local.contributor.authoruid | Tha Hla, Ron, u7700418 | |
| local.description.embargo | 2037-12-31 | |
| local.description.notes | Imported from ARIES | |
| local.description.refereed | Yes | |
| local.identifier.absfor | 110704 - Cellular Immunology | |
| local.identifier.ariespublication | MigratedxPub3506 | |
| local.identifier.citationvolume | 169 | |
| local.identifier.scopusID | 2-s2.0-0036644271 | |
| local.type.status | Published Version |
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