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Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis

dc.contributor.authorMullbacher, Arno
dc.contributor.authorLobigs, Mario
dc.contributor.authorTha Hla, Ron
dc.contributor.authorTran, Thao (Thomas)
dc.contributor.authorStehle, Thomas
dc.contributor.authorSimon, Markus M
dc.date.accessioned2015-12-13T22:24:54Z
dc.date.issued2002
dc.date.updated2015-12-11T08:11:31Z
dc.description.abstractEffector cytolytic T (Tc) lymphocytes, deficient in the exocytosis-mediated pathway of target cell lysis, induce Fas on target cells and, in turn, delayed cell death and apoptosis via the Fas ligand-Fas interaction. The induction of Fas can be blocked by
dc.identifier.issn0022-1767
dc.identifier.urihttp://hdl.handle.net/1885/72973
dc.publisherAmerican Association of Immunologists
dc.sourceJournal of Immunology
dc.subjectKeywords: antibody; Fas antigen; FAS ligand; major histocompatibility antigen; recombinant gamma interferon; T lymphocyte receptor; animal cell; apoptosis; article; bystander effect; cell death; cytolysis; cytotoxic T lymphocyte; effector cell; exocytosis; knockout
dc.titleAntigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis
dc.typeJournal article
local.bibliographicCitation.lastpage150
local.bibliographicCitation.startpage145
local.contributor.affiliationMullbacher, Arno, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLobigs, Mario, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationTha Hla, Ron, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationTran, Thao (Thomas), Victorian Infectious Diseases Reference Laboratory
local.contributor.affiliationStehle, Thomas, Max Planck Institute of Immunobiology
local.contributor.affiliationSimon, Markus M, Max Planck Institute of Immunobiology
local.contributor.authoruidMullbacher, Arno, u8102295
local.contributor.authoruidLobigs, Mario, u8506091
local.contributor.authoruidTha Hla, Ron, u7700418
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor110704 - Cellular Immunology
local.identifier.ariespublicationMigratedxPub3506
local.identifier.citationvolume169
local.identifier.scopusID2-s2.0-0036644271
local.type.statusPublished Version

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