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A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

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Date

2010

Authors

Arcos-Burgos, Mauricio
Jain, M.
Acosta, M. T.
Shively, S.
Stanescu, H.
Wallis, D.
Domene, S.
Velez, Jorge I.
Karkera, J. D.
Muenke, Maximilian

Journal Title

Journal ISSN

Volume Title

Publisher

Nature Publishing Group

Abstract

Attention-Deficit/Hyperactivity Disorder (ADHD) has a very high heritability (0.8), suggesting that about 80% of phenotypic variance is due to genetic factors. We used the integration of statistical and functional approaches to discover a novel gene that

Description

Keywords

Keywords: central stimulant agent; adolescent; attention deficit disorder; child; family history; gene; gene function; gene mapping; genetic association; genetic predisposition; human; human tissue; immunohistochemistry; latrophilin 3 gene; major clinical study; ph ADHD; complex trait; gene; genetics; latrophilin; LPHN3

Citation

URI

http://hdl.handle.net/1885/84919

Collections

ANU Research Publications

Source

Molecular Psychiatry

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1038/mp.2010.6

Restricted until

2037-12-31

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