The NF-κB transcription factor c-Rel is required for Th17 effector cell development in experimental autoimmune encephalomyelitis
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Chen, Guobing
Hardy, Kristine
Pagler, Eloisa
Ma, Lina
Lee, Seung Soo
Gerondakis, Steve
Daley, Stephen
Shannon, M Frances
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American Association of Immunologists
Abstract
Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated autoimmune disease involving effector Th subsets such as Th1 and Th17. In this study, we demonstrate that mice lacking the NF-κB transcription factor family member c-Rel (rel -/-), whic
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Journal of Immunology
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2037-12-31
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