Lysophosphatidic Acid Activates the 70-kDa S6 Kinase via the Lipoxygenase Pathway

Date

2001

Authors

Willard, Francis
Berven, Leise
Crouch, Michael

Journal Title

Journal ISSN

Volume Title

Publisher

Academic Press

Abstract

Many hormones are known to activate the 70-kDa S6 kinase (p70S6K). The signalling pathways mediating p70S6K activation are only partially characterized. We investigate, in this report, the mechanisms by which lysophosphatidic acid (LPA) activates p70S6K.

Description

Keywords

Keywords: 2 butanol; arachidonic acid; butanol; calcium ion; G protein coupled receptor; lipoxygenase; lysophosphatidic acid; phosphatidylinositol 3 kinase; phospholipase A2; phospholipase C; phospholipase D; protein kinase C; rapamycin; S6 kinase; actin polymeriza 70-kDa S6 kinase; Arachidonic acid; Lipoxygenase; Lysophosphatidic acid; Phospholipase A2; Phospholipase C; Phospholipase D; Protein kinase C

Citation

Source

Biochemical and Biophysical Research Communications

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31