Cyclodextrins to limit substrate inhibition and alter substrate selectivity displayed by enzymes
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Easton, Christopher
Harper, Jason B
Head, Sarah
Lee, Kitty
Lincoln, Stephen F
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Royal Society of Chemistry
Abstract
The substrate inhibition exhibited by carboxypeptidase A in catalysing the hydrolysis of (S)-2-O-(N-benzoylglycyl)β-phenyllactate) is limited by addition of cyclodextrins. The cyclodextrins do not significantly change the maximum rate of reaction, but th
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Journal of the Chemical Society, Perkin Transactions 1