TLR2-targeted secreted proteins from Mycobacterium tuberculosis are protective as powdered pulmonary vaccines

Tyne, Anneliese S.; Chan, John Gar Yan; Shanahan, Erin R.; Atmosukarto, Ines; Chan, Hak-Kim; Britton, Warwick; West, Nicholas P.

TLR2-targeted secreted proteins from Mycobacterium tuberculosis are protective as powdered pulmonary vaccines

Date

2013

Authors

Tyne, Anneliese S.

Chan, John Gar Yan

Shanahan, Erin R.

Atmosukarto, Ines

Chan, Hak-Kim

Britton, Warwick

West, Nicholas P.

Publisher

Elsevier

Abstract

Despite considerable research efforts towards effective treatments, tuberculosis (TB) remains a staggering burden on global health. Suitably formulated sub-unit vaccines offer potential as safe and effective generators of protective immunity. The Mycobact