A Key Role for TGF-beta Signaling to T Cells in the Long-Term Acceptance of Allografts

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Daley, Stephen
Ma, Jianbo
Adams, Elisabeth
Cobbold, Stephen P
Waldmann, Hermann

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American Association of Immunologists

Abstract

TGF-β is a key immunoregulatory cytokine which supports self-tolerance by signaling to T cells. In this report, we show a crucial role for TGF-β signaling to T cells in enabling the long-term acceptance of allografts, whether natural or induced therapeu

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Journal of Immunology

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2037-12-31