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Heparanase is involved in the pathogenesis of proteinuria as a result of glomerulonephritis

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Date

2004

Authors

Levidiotis, Vicki
Freeman, Craig
Tikellis, Chris
Cooper, Mark E
Power, David A

Journal Title

Journal ISSN

Volume Title

Publisher

Williams & Wilkins

Abstract

The β-D-endoglycosidase heparanase has been proposed to be important in the pathogenesis of proteinuria by selectively degrading the negatively charged side chains of heparan sulfate proteoglycans within the glomerular basement membrane. A loss of negati

Description

Keywords

Keywords: beta dextro endoglycosidase; complement; enzyme antibody; enzyme precursor; glycosidase; growth factor; heparanase; immunoglobulin G; messenger RNA; polyclonal antibody; proteoheparan sulfate; sodium chloride; unclassified drug; animal cell; animal experi

Citation

URI

http://hdl.handle.net/1885/87775

Collections

ANU Research Publications

Source

Journal of the American Society of Nephrology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1097/01.ASN.0000103229.25389.40

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