Treatment of pulmonary hypertension with sildenafil in a neonate with Spondyloepiphyseal Dysplasea Congenita

Abstract

Persistent pulmonary hypertension of the newborn (PPHN) remains an important cause of mortality and morbidity in the term neonate. Preliminary but limited data suggest that there may be a role for sildenafil in the treatment of PPHN. We report the successful treatment of PPHN caused by pulmonary hypoplasia in a patient with spondyloepiphyseal dysplasia congenita. Show more