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Calciphylaxis in a dialysis patient successfully treated with high-dose vitamin K supplementation

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dc.contributor.authorChristiadi, D
dc.contributor.authorSinger, Richard
dc.date.accessioned2022-02-07T23:17:07Z
dc.date.available2022-02-07T23:17:07Z
dc.date.issued2018
dc.date.updated2020-12-13T07:21:07Z
dc.description.abstractCalciphylaxis has high mortality. Vitamin K deficiency is common in haemodialysis patients and may be a trigger for calciphylaxis due to its role in activating matrix Gla protein (a tissue inhibitor of calcification). We report the case of a 43-year-old female haemodialysis patient who developed calciphylaxis. Two months prior to the diagnosis she was found to have an undetectable plasma vitamin K concentration. The calciphylaxis completely resolved with vitamin K supplementation and an increase in haemodialysis frequency. She did not receive sodium thiosulphate or bisphosphonates. Supplementation of vitamin K in deficient patients may improve the outcome of this condition.en_AU
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn1753-0792en_AU
dc.identifier.urihttp://hdl.handle.net/1885/259553
dc.language.isoen_AUen_AU
dc.provenanceThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.comen_AU
dc.publisherOxford University Pressen_AU
dc.rights© The Author 2017. Published by Oxford University Press on behalf of ERA-EDTAen_AU
dc.rights.licenseCreative Commons Attribution Non-Commercial Licenseen_AU
dc.rights.urihttp://creativecommons.org/ licenses/by-nc/4.0/en_AU
dc.sourceClinical Kidney Journalen_AU
dc.subjectcalciphylaxisen_AU
dc.subjectmalabsorptionen_AU
dc.subjectmatrix Gla proteinen_AU
dc.subjectrenal dialysisen_AU
dc.subjectvitamin Ken_AU
dc.titleCalciphylaxis in a dialysis patient successfully treated with high-dose vitamin K supplementationen_AU
dc.typeJournal articleen_AU
dcterms.accessRightsOpen Accessen_AU
local.bibliographicCitation.issue4en_AU
local.bibliographicCitation.lastpage529en_AU
local.bibliographicCitation.startpage528en_AU
local.contributor.affiliationChristiadi, D, The Canberra Hospitalen_AU
local.contributor.affiliationSinger, Richard, College of Health and Medicine, ANUen_AU
local.contributor.authoruidSinger, Richard, a304487en_AU
local.description.notesImported from ARIESen_AU
local.identifier.absfor110312 - Nephrology and Urologyen_AU
local.identifier.absseo920106 - Endocrine Organs and Diseases (excl. Diabetes)en_AU
local.identifier.ariespublicationu3102795xPUB2569en_AU
local.identifier.citationvolume11en_AU
local.identifier.doi10.1093/ckj/sfx126en_AU
local.identifier.thomsonIDWOS:000449491000014
local.publisher.urlhttp://ndtplus.oxfordjournals.org/en_AU
local.type.statusPublished Versionen_AU

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