Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus

Date

Authors

Lee, Eva

Lobigs, Mario

Publisher

American Society for Microbiology

Abstract

The in vivo mechanism for virulence attenuation of laboratory-derived variants of two flaviviruses in the Japanese encephalitis virus (JEV) serocomplex is described. Host cell adaptation of JEV and Murray Valley encephalitis virus (MVE) by serial passage

Keywords

Keywords: amino acid; aspartic acid; encephalitis vaccine; envelope protein; Gag protein; glutamine; glycosaminoglycan; heparin; animal cell; animal experiment; animal model; animal tissue; article; binding affinity; controlled study; encephalitis virus; extracellu

URI

http://hdl.handle.net/1885/70599

Collections

ANU Research Publications

Source

Journal of Virology

Type

Journal article

DOI

10.1128/JVI.76.10.4901-4911.2002

Restricted until

2037-12-31

Downloads

File

Description

01_Lee_Mechanism_of_virulence_2002.pdf (169.4 KB)

02_Lee_Mechanism_of_virulence_2002.pdf (225.02 KB)