Influence of Protein Flexibility on the Electrostatic Energy Landscape in Gramicidin A

Date

Authors

Corry, Ben

Chung, Shin-Ho

Publisher

Springer

Abstract

We describe an electrostatic model of the gramicidin A channel that allows protein atoms to move in response to the presence of a permeating ion. To do this, molecular dynamics simulations are carried out with a permeating ion at various positions within

Keywords

Keywords: gramicidin A; ion channel; article; atom; calculation; conductance; electricity; energy; molecular dynamics; protein structure; simulation; statistical significance; Computer Simulation; Diffusion; Elasticity; Electrostatics; Energy Transfer; Gramicidin; Brownian dynamics; Conductance; Electrostatics; Gramicidin A; Ion channels; Ion permeation; Molecular dynamics; Protein motion; Simulation

URI

http://hdl.handle.net/1885/83451

Collections

ANU Research Publications

Source

European Biophysics Journal

Type

Journal article

DOI

10.1007/s00249-004-0442-z

Restricted until

2037-12-31

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Description

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