Estimating Vaccine Efficacy from small outbreaks

Becker, Niels; Britton, Tom

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Estimating Vaccine Efficacy from small outbreaks

Date

2004

Authors

Becker, Niels

Britton, Tom

Publisher

Biometrika Trust

Abstract

Let CV and C0 denote the number of cases among vaccinated and unvaccinated individuals, respectively, and let v be the proportion of individuals vaccinated. The quantity ê = 1 -(1-v)C V/(vC0) = 1 -(relative attack rate) is the most used estimator of the