Causes of death in infants admitted to Australian neonatal intensive care units between 1995 and 2006

Date

2013

Authors

Feng, Yvonne
Mohamed, Abdel-Latif
Bajuk, Barbara
Lui, Kei
Oei, Ju Lee

Journal Title

Journal ISSN

Volume Title

Publisher

Wiley-Blackwell

Abstract

Aim To compare causes and rates of mortality among infants admitted to 10 Australian neonatal intensive care units (NICUs) between 1995 and 2006. Methods: De-identified perinatal data from the Neonatal Intensive Care Units' (NICUS) Data Collection for 24131 infants were examined for causes and rates of death. The study period was divided into two epochs: I (1995-2000, n=11185 infants) and II (2001-2006, n=12946 infants). Results: A total of 2224 (9.2%) infants died in hospital. Mortality decreased from 10.3% (1152/11185) in epoch I to 8.3% (1072/12946) in epoch II (p<0.001) due to improved survival in term infants. Extreme prematurity also decreased as a primary cause of death (118 (10.2%) vs 76 (7.1%), p=0.008). No infant >42-week gestation was admitted in epoch II. Congenital abnormalities were the most common cause of death (>20%) in both epochs, mostly in term rather than preterm infants (40.7% vs 13.9%, p<0.001). Age of death was unchanged between the two epochs (median 4, 1st, 3rd quartiles: 1,16days). Conclusion: Mortality rates have continued to decrease but improvement is predominantly due to improved survival of term infants and prevention of postdate deliveries. Congenital abnormalities continue to be the most common cause of death.

Description

Keywords

Keywords: Aborigine; antepartum hemorrhage; article; Australia; birth weight; brain hemorrhage; cause of death; cesarean section; chronic lung disease; congenital disorder; corticosteroid therapy; female; gestational age; head circumference; hospital discharge; hum Causes and rates; Mortality; Neonatal intensive care; Trends

Citation

Source

Acta Paediatrica

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1111/apa.12039

Restricted until

2037-12-31