A/T-targeted somatic hypermutation: critique of the mainstream model
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Blanden, Robert
Franklin, Andrew
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Elsevier
Abstract
The 'affinity maturation' of the humoral immune response is driven by antigen-activated somatic hypermutation (SHM) of the genes that encode antibody variable regions and the subsequent antigenic selection of mutant clones. The molecular mechanism of SHM
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Trends in Biochemical Sciences
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2037-12-31
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