A simple regiospecific strategy for labelling hydrogen atoms in a-amino acids

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Pearce, Dierdre
Hammershoi, Anders
Harrowfield, Jack M
Sargeson, Alan

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Royal Society of Chemistry

Abstract

Simple methods for the regioselective introduction of deuterium labels at the α- and β-carbon atoms of leucine using a Co(III) imino acid complex are described which have a general applicability to the synthesis of a range of labelled amino acids.

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Chemical Communications

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