A simple regiospecific strategy for labelling hydrogen atoms in a-amino acids

Pearce, Dierdre; Hammershoi, Anders; Harrowfield, Jack M; Sargeson, Alan

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A simple regiospecific strategy for labelling hydrogen atoms in a-amino acids

Date

2000

Authors

Pearce, Dierdre

Hammershoi, Anders

Harrowfield, Jack M

Sargeson, Alan

Publisher

Royal Society of Chemistry

Abstract

Simple methods for the regioselective introduction of deuterium labels at the α- and β-carbon atoms of leucine using a Co(III) imino acid complex are described which have a general applicability to the synthesis of a range of labelled amino acids.

Keywords

Keywords: alpha amino acid; deuterium; leucine; amino acid synthesis; article; complex formation; isotope labeling; molecular interaction; polymerization

URI

http://hdl.handle.net/1885/89595

Collections

ANU Research Publications

Source

Chemical Communications

Type

Journal article

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A simple regiospecific strategy for labelling hydrogen atoms in a-amino acids

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