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A unique T cell receptor discovered in marsupials

Date

Authors

Parra, Zuly E

Baker, Michelle L

Schwarz, Ryan

Deakin, Janine

Lindblad-Toh, Kerstin

Miller, Robert D

Publisher

National Academy of Sciences (USA)

Abstract

T cells recognize antigens by using T cell receptors (TCRs) encoded by gene segments, called variable (V), diversity (D), and joining (J), that undergo somatic recombination to create diverse binding specificities. Four TCR chains (α, β, γ, and δ) hav

Keywords

Keywords: messenger RNA; T lymphocyte receptor; T lymphocyte receptor alpha chain; T lymphocyte receptor beta chain; T lymphocyte receptor delta chain; T lymphocyte receptor gamma chain; T lymphocyte receptor mu chain; unclassified drug; antigen recognition; articl Evolution; Immune system

URI

http://hdl.handle.net/1885/17172

Collections

ANU Research Publications

Source

PNAS - Proceedings of the National Academy of Sciences of the United States of America

Type

Journal article

DOI

10.1073/pnas.0609106104

Restricted until

2037-12-31

Downloads

File

Description

01_Parra_A_unique_T_cell_receptor_2007.pdf (1.53 MB)