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Vitamin B3 levels in women who experience first‐trimester miscarriage

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dc.contributor.authorYakob, Nural Aini
dc.contributor.authorPeek, Michael
dc.contributor.authorQuinlivan, Julie
dc.date.accessioned2022-08-10T01:36:40Z
dc.date.issued2021
dc.date.updated2021-08-01T08:28:00Z
dc.description.abstractMiscarriage is the most common complication in early pregnancy. It was recently reported in mice that miscarriage can be prevented through the administration of niacin. We conducted a prospective, exploratory pilot study involving 24 women who were less than 14 weeks pregnant. Neither niacin intake (P = 0.24) nor urinary vitamin B3 measured as the 1‐methyl‐5‐carboxylamide‐2‐pyridone/N‐1‐methylnicotinamide (2‐pyr/MNA) ratio (P = 1.00) predicted miscarriage. However, the difference in mean 2‐pyr/MNA ratios between women who miscarried and controls suggests there may be a threshold niacin level protective in miscarriage prevention warranting further investigation.en_AU
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn0004-8666en_AU
dc.identifier.urihttp://hdl.handle.net/1885/270338
dc.language.isoen_AUen_AU
dc.publisherWileyen_AU
dc.rights© 2021 The Royal Australian and New Zealand College of Obstetricians and Gynaecologistsen_AU
dc.sourceAustralian and New Zealand Journal of Obstetrics and Gynaecologyen_AU
dc.subjectfood diaryen_AU
dc.subjectmiscarriageen_AU
dc.subjectniacinen_AU
dc.subjectpregnancyen_AU
dc.subjectvitamin B3en_AU
dc.titleVitamin B3 levels in women who experience first‐trimester miscarriageen_AU
dc.typeJournal articleen_AU
local.bibliographicCitation.issue3en_AU
local.bibliographicCitation.lastpage483en_AU
local.bibliographicCitation.startpage478en_AU
local.contributor.affiliationYakob, Nural Aini, College of Health and Medicine, ANUen_AU
local.contributor.affiliationPeek, Michael, College of Health and Medicine, ANUen_AU
local.contributor.affiliationQuinlivan, Julie, College of Health and Medicine, ANUen_AU
local.contributor.authoruidYakob, Nural Aini, u6620470en_AU
local.contributor.authoruidPeek, Michael, u1005089en_AU
local.contributor.authoruidQuinlivan, Julie, u1056872en_AU
local.description.embargo2099-12-31
local.description.notesImported from ARIESen_AU
local.identifier.absfor000000 - Internal ANU use onlyen_AU
local.identifier.ariespublicationu3402575xPUB25en_AU
local.identifier.citationvolume61en_AU
local.identifier.doi10.1111/ajo.13341en_AU
local.identifier.essn1479-828Xen_AU
local.identifier.scopusID2-s2.0-85104309633
local.publisher.urlhttps://www.wiley.com/en-gben_AU
local.type.statusPublished Versionen_AU

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