Convergent synthesis and preliminary biological evaluation of (+)-B-norrhazinal

Banwell, Martin; Edwards, Alison; Smith, Jeremy; Hamel, Ernest; Verdier-Pinard, Pascal

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Convergent synthesis and preliminary biological evaluation of (+)-B-norrhazinal

Date

2000

Authors

Banwell, Martin

Edwards, Alison

Smith, Jeremy

Hamel, Ernest

Verdier-Pinard, Pascal

Publisher

Royal Society of Chemistry

Abstract

The title compound 3, an analogue of the naturally-derived spindle toxin rhazinilam (1), has been synthesised, characterised crystallographically and subjected to a preliminary biological evaluation.