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Association of the androgen receptor CAG repeat polymorphism with Alzheimer's disease in men

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Date

2003

Authors

Lehmann, D
Butler, H T
Warden, D R
Combrink, M
King, E
Nicoll, J
Budge, Marc
de Jager, Celeste A
Hogervorst, E
Esiri, M M

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

We examined the CAG repeat polymorphism in exon 1 of the androgen receptor (AR) in an Oxford cohort of 150 cases (101 men) of definite or probable Alzheimer's disease (AD) and 190 elderly controls (140 men). We found that short alleles (≤20 CAG repeats)

Description

Keywords

Keywords: adult; allele; Alzheimer disease; article; cohort analysis; confidence interval; controlled study; disease association; exon; genetic polymorphism; human; major clinical study; male; onset age; priority journal; risk factor; Aged; Aged, 80 and over; Allel Apolipoprotein E e4; Butyrylcholinesterase K variant; Estrogen; Gender; Neuroprotection; Sex steroids; Testosterone; X chromosome

Citation

URI

http://hdl.handle.net/1885/77029

Collections

ANU Research Publications

Source

Neuroscience Letters

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/S0304-3940(03)00069-7

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