Interaction of the antitumor antibiotic streptonigrin with DNA and oligonucleotides
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Authors
Long, Georgina V
Harding, Margaret
Fan, J Y
Denny, W A
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Cognizant Communication Corporation
Abstract
The interaction of the aminoquinone antitumour antibiotic streptonigrin with plasmid DNA, calf thymus DNA and oligonucleotides, in the presence and absence of metal ions, has been studied using circular dichroism, NMR spectroscopy and gel electrophoresis
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Anti-Cancer Drug Design