A Model of Sodium Channels

Date

Authors

Vora, Taira

Corry, Ben

Chung, Shin-Ho

Publisher

Elsevier

Abstract

We have explored the permeation and blockage of ions in sodium channels, relating the channel structure to function using electrostatic profiles and Brownian dynamics simulations. The model used resembles the KcsA potassium channel with an added external

Keywords

Keywords: amino acid; calcium ion; ion; potassium; potassium channel; sodium; sodium channel; article; electric potential; electricity; model; Poisson distribution; priority journal; simulation; Calcium; Cations; Electrostatics; Ion Channel Gating; Models, Biologic Blockage; Brownian dynamics; Electrostatics; Ion channel; Permeation; Selectivity; Sodium channel

URI

http://hdl.handle.net/1885/83357

Collections

ANU Research Publications

Source

Biochimica et Biophysica Acta: Biomembranes

Type

Journal article

DOI

10.1016/j.bbamem.2004.11.011

Restricted until

2037-12-31

Downloads

File

Description

01_Vora_A_Model_of_Sodium_Chan_2005.pdf (407.31 KB)