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A novel one-pot domino reaction for the synthesis of 2-acetyl-3-(phenylamino)indolizine-1-carboxamide derivatives

Date

Authors

Ziyaadini, Morteza

Hazeri, Nourallah

Maghsoodlou, Malek Taher

Habibi-Khorassani, Sayyed Mostafa

Willis, Anthony

Publisher

Elsevier

Abstract

2-Acetyl-3-(phenylamino)indolizine-1-carboxamide derivatives were obtained via a one-pot domino reaction of alkyl or aryl isocyanides and pyridine-2-carbaldehyde in the presence of acetoacetanilide in toluene without any prior activation or modification.

Keywords

Keywords: 2 acetyl 3 (phenylamino)indolizine 1 carboxamide derivative; acetanilide derivative; amide; cyanide; pyridine derivative; toluene; unclassified drug; article; chemical reaction; drug structure; drug synthesis Acetoacetanilide; Indolizine derivatives; Isocyanide; One-pot reaction; Pyridine-2-carbaldehyde

URI

http://hdl.handle.net/1885/60315

Collections

ANU Research Publications

Source

Tetrahedron Letters

Type

Journal article

DOI

10.1016/j.tetlet.2011.08.118

Restricted until

2037-12-31

Downloads

File

Description

01_Ziyaadini_A_novel_one-pot_domino_2011.pdf (306.2 KB)

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