Acute Oxygen Supplementation Restores Markers of Hepatocyte Energy Status and Hypoxia in Cirrhotic Rats

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Harvey, Peta
Gready, Jill
Yin, Zhan-Li
Le Couteur, D
McLean, Allan

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American Society for Pharmacology and Experimental Therapeutics

Abstract

The oxygen limitation hypothesis states that hepatocyte hypoxia is the mechanism determining metabolic restriction in the cirrhotic liver. Therefore we studied markers of hepatocyte energy state and cellular hypoxia in livers of normal and cirrhotic rats

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Journal of Pharmacology and Experimental Therapeutics

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2037-12-31