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Effective tumor targeting and enhanced anti-tumor effect of liposomes engrafted with peptides specific for tumor lymphatics and vasculature

Date

2011

Authors

Herringson, Thomas
Altin, Joseph

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

The use of liposomes to target drugs to tumors represents an attractive therapeutic strategy, especially when used with convenient targeting moieties such as peptides. Here we explored several peptides for their ability to target liposomes to tumors. The

Description

Keywords

Keywords: doxorubicin; liposome; macrogol derivative; metal chelate; neuropilin 1; nitrilotriacetic acid ditetradecyclamine; phosphatidylethanolamine polyethylene glycol; tumor marker; unclassified drug; vascular targeting agent; vasculotropin receptor 1; antineopl Chelator lipid; Doxorubicin; Drug delivery; Stealth liposomes; Targeting peptide; Vasculature

Citation

Source

International Journal of Pharmaceutics

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31
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