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Effective tumor targeting and enhanced anti-tumor effect of liposomes engrafted with peptides specific for tumor lymphatics and vasculature

Date

Authors

Herringson, Thomas

Altin, Joseph

Publisher

Elsevier

Abstract

The use of liposomes to target drugs to tumors represents an attractive therapeutic strategy, especially when used with convenient targeting moieties such as peptides. Here we explored several peptides for their ability to target liposomes to tumors. The

Keywords

Keywords: doxorubicin; liposome; macrogol derivative; metal chelate; neuropilin 1; nitrilotriacetic acid ditetradecyclamine; phosphatidylethanolamine polyethylene glycol; tumor marker; unclassified drug; vascular targeting agent; vasculotropin receptor 1; antineopl Chelator lipid; Doxorubicin; Drug delivery; Stealth liposomes; Targeting peptide; Vasculature

URI

http://hdl.handle.net/1885/69396

Collections

ANU Research Publications

Source

International Journal of Pharmaceutics

Type

Journal article

DOI

10.1016/j.ijpharm.2011.03.044

Restricted until

2037-12-31

Downloads

File

Description

01_Herringson_Effective_tumor_targeting_and_2011.pdf (870.54 KB)

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