Multicomponent coupling approach to (�)-frondosin B and a ring-expanded analogue
Date
2004
Authors
Kerr, Daniel
Willis, Anthony
Flynn, Bernard
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Volume Title
Publisher
American Chemical Society
Abstract
(Equation presented) A recently discovered multicomponent coupling reaction is used to give direct access to a late intermediate in the synthesis of frondosin B. This intermediate can also be efficiently converted to a ring-expanded analogue of frondosin
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Keywords
Keywords: frondosin b; hydrogen; palladium; sesquiterpene derivative; unclassified drug; article; chemical reaction; cyclization; drug structure; drug synthesis; heating; Animals; Catalysis; Cyclization; Heterocyclic Compounds with 4 or More Rings; Indicators and R
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Source
Organic Letters
Type
Journal article
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2037-12-31
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