Active care of infants born between 22 and 26 weeks of gestation does not follow consensus expert recommendations **

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Sinclair, Ruth
Bajuk, Barbara
Guaran, R
Challis, D
Sheils, Joanne
Mohamed, Abdel-Latif
Hilder, Lisa
Wright, Ian M
Oei, Ju Lee

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Wiley-Blackwell

Abstract

Aim To determine the relationship between clinical practice and publication of an Australian consensus statement for management of extremely preterm infants in 2006. Methods A population‐based study using linked data from New South Wales, Australia for births between 22 + 0 and 26 + 6 weeks of gestation between 2000 and 2011. Results There were 4746 births of whom 2870 were liveborn and 1876 were stillborn. Of the live births, 2041 (71%) were resuscitated, 1914 (67%) were admitted into a neonatal intensive care unit (NICU) and 1310 (46%) survived to hospital discharge. Thirty‐nine (2%) stillbirths were resuscitated but none survived. No 22‐week infant survived to hospital discharge. Fewer 23‐week gestation infants were resuscitated between 2004 (52%) and 2005 (20%) but resuscitation rates increased by 2008 (44%). There was no difference at other gestations. Adjusted odds ratio (OR) for resuscitation was increased by birthweight (OR: 1.01), tertiary hospital birth (OR: 3.4) and Caesarean delivery (OR: 11.3) and decreased by rural residence (OR: 0.4) and male gender (OR: 0.7). Conclusion Expert recommendations may be shaped by clinical practice rather than the converse, especially for 23‐week gestation infants. Recommendations should be revised regularly to include clinical practice changes.

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Acta Paediatrica

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Restricted until

2099-12-31