Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

Date

2009

Authors

Martin, Rowena
Marchetti, Rosa
Cowan, Anna
Howitt, Susan
Broer, Stefan
Kirk, Kiaran

Journal Title

Journal ISSN

Volume Title

Publisher

American Association for the Advancement of Science

Abstract

The emergence and spread of chloroquine-resistant Plasmodium falciparum malaria parasites has been a disaster for world health. Resistance is conferred by mutations in the Chloroquine Resistance Transporter (PfCRT), an integral membrane protein localized

Description

Keywords

Keywords: amantadine; amodiaquine; artemisinin; chloroquine; piperaquine; quinine; verapamil; digestive system disorder; disease resistance; disease transmission; gene expression; health care; malaria; membrane; mutation; protein; acidity; article; binding site; co

Citation

Source

Science

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31