Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter
Date
2009
Authors
Martin, Rowena
Marchetti, Rosa
Cowan, Anna
Howitt, Susan
Broer, Stefan
Kirk, Kiaran
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Publisher
American Association for the Advancement of Science
Abstract
The emergence and spread of chloroquine-resistant Plasmodium falciparum malaria parasites has been a disaster for world health. Resistance is conferred by mutations in the Chloroquine Resistance Transporter (PfCRT), an integral membrane protein localized
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Keywords
Keywords: amantadine; amodiaquine; artemisinin; chloroquine; piperaquine; quinine; verapamil; digestive system disorder; disease resistance; disease transmission; gene expression; health care; malaria; membrane; mutation; protein; acidity; article; binding site; co
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Science
Type
Journal article
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Restricted until
2037-12-31
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