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Finite element simulation of the gating mechanism of mechanosensitive ion channels

Date

Authors

Bavi, Navid

Qin, Qing Hua

Martinac, Boris

Publisher

SPIE - The International Society for Optical Engineering

Abstract

In order to eliminate limitations of existing experimental or computational methods (such as patch-clamp technique and molecular dynamics analysis, respectively) a finite element (FE) model for multi length-scale and time-scale investigation of the gating

Keywords

Keywords: Artificial membranes; Cholesterol content; Finite element simulations; Gating mechanisms; Mechanosensitive ion channels; MscL; Patch clamp technique; Trans-membrane proteins; Cell membranes; Cytology; Elastic moduli; Escherichia coli; Finite element metho finite element method; gating mechanism; lipid bilayer; mechanosensitive ion channels; MscL

URI

http://hdl.handle.net/1885/82630

Collections

ANU Research Publications

Source

Proceedings of SPIE - The International Society for Optical Engineering

Type

Conference paper

DOI

10.1117/12.2030203

Restricted until

2037-12-31

Downloads

File

Description

01_Bavi_Finite_element_simulation_of_2013.pdf (1.56 MB)