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Type 2 diabetes mellitus, cognition and brain in aging: a brief review

dc.contributor.authorKumar, Rajeev
dc.contributor.authorLooi, Jeffrey
dc.contributor.authorRaphael, Beverley
dc.date.accessioned2009-11-02T00:28:08Zen_US
dc.date.accessioned2010-12-20T06:03:14Z
dc.date.available2009-11-02T00:28:08Zen_US
dc.date.available2010-12-20T06:03:14Z
dc.date.issued2009-01en_US
dc.date.updated2021-08-01T08:21:02Z
dc.description.abstractDiabetes mellitus is a complex disease with many potential complications. Whilst there have been inconsistent results in regard to an association between cognition and type 2 diabetes, there is evidence that verbal memory and processing speed are the cognitive domains usually impaired. In elderly diabetic subjects, other cognitive domains may also be involved, due to ageing. Glycemic control is implicated in the development of cognitive dysfunction, although more research is needed in this area. Insulin dysregulation and hyperglycemia play an important role in neurodegeneration. Using structural neuroimaging, it has been shown that brain atrophy is an important feature in those with type 2 diabetes. Integrative research is needed using behavioral, cognitive, imaging, and genetic platforms.
dc.description.sponsorshipCopyright Information: http://www.sherpa.ac.uk/romeo/search.php "Author can archive pre-print (ie pre-refereeing) … post-print (ie final draft post-refereeing) … [and] publisher's version/PDF … [on] non-commercial [sites]" - SHERPA/RoMEO site (as at 19/05/10)
dc.format4 pages
dc.identifier.citationIndian Journal of Psychiatry 51 (2009): S35-8
dc.identifier.issn0019-5545en_US
dc.identifier.issn1998-3794en_US
dc.identifier.urihttp://hdl.handle.net/10440/986en_US
dc.identifier.urihttp://digitalcollections.anu.edu.au/handle/10440/986
dc.publisherMedknow Publications
dc.rightshttp://www.sherpa.ac.uk/romeo/search.php "Author can archive pre-print (ie pre-refereeing) … post-print (ie final draft post-refereeing) … [and] publisher's version/PDF … [on] non-commercial [sites]" - SHERPA/RoMEO site (as at 19/05/10)
dc.sourceIndian Journal of Psychiatry
dc.source.urihttp://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2009;volume=51;issue=5;spage=35;epage=38;aulast=Kumaren_US
dc.subjectbrain atrophy
dc.subjectcognition
dc.subjectdiabetes mellitus
dc.subjectmagnetic resonance imaging
dc.subjectneurodegeneration
dc.titleType 2 diabetes mellitus, cognition and brain in aging: a brief review
dc.typeJournal article
local.bibliographicCitation.issueSupplement January 2009
local.bibliographicCitation.lastpage38
local.bibliographicCitation.startpages35
local.contributor.affiliationKumar, Rajeev, School of Health and Psychological Sciences, ANU Medical Schoolen_US
local.contributor.affiliationLooi, Jeffrey, School of Health and Psychological Sciences, ANU Medical Schoolen_US
local.contributor.affiliationRaphael, Beverley, School of Health and Psychological Sciences, ANU Medical Schoolen_US
local.contributor.authoruidu3923137en_US
local.contributor.authoruida154704en_US
local.contributor.authoruida220119en_US
local.description.notesThis is an invited article.en_US
local.identifier.absfor170102en_US
local.identifier.ariespublicationa154704xPUB1en_US
local.identifier.citationvolume51
local.type.statusPublished Versionen_US

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