Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance

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Authors

Parish, Ian
Waithman, Jason
Davey, Gayle M
Belz, Gabrielle
Mintern, Justine
Kurts, Christian
Sutherland, Robyn
Carbone, Francis
Heath, William R

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National Academy of Sciences (USA)

Abstract

Autoimmune diseases tend to be chronic and progressive, but how these responses are sustained is not clear. One cell type that might contribute to autoimmunity is the cytotoxic T lymphocyte (CTL), which, as a consequence of causing tissue destruction and

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PNAS - Proceedings of the National Academy of Sciences of the United States of America

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Restricted until

2037-12-31