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miRNAs in Cardiac Disease: sitting duck or moving target?

Date

Authors

Hynes, Carly

Clancy, Jennifer

Preiss, Thomas

Publisher

Taylor & Francis Group

Abstract

Emerging findings indicate that cells can produce both micro (mi)RNAs and their messenger (m)RNA targets in multiple processing variants in a tissue- and developmental stage-selective manner. Specifically, we find that cells accumulate a greater range of

Keywords

Keywords: messenger RNA; microRNA; microRNA 21; microRNA 22; cardiovascular function; gene expression; gene function; genetic analysis; heart; heart disease; human; review; RNA processing; Animals; Gene Expression Regulation; Heart Diseases; Humans; MicroRNAs 3' untranslated region; cardiac disease; miRNA biogenesis; miRNA-target interaction; mRNA 3' end cleavage; polyadenylation

URI

http://hdl.handle.net/1885/20101

Collections

ANU Research Publications

Source

IUBMB Life

Type

Journal article

DOI

10.1002/iub.1082

Restricted until

2037-12-31

Downloads

File

Description

01_Hynes_miRNAs_in_Cardiac_Disease:__2012.pdf (375.03 KB)