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Solvent-Free Synthesis of Cyanoformamides from Carbamoyl Imidazoles

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Authors

Nugent, Jeremy
Campbell, Sarah
VO, Yen Thi-Hoang
Schwartz, Brett

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Wiley-VCH Verlag GMBH

Abstract

A straightforward and solvent-free synthesis of various secondary and tertiary cyanoformamides from carbamoyl imidazoles and TMSCN has been developed. Both cyclic and acyclic carbamoyl imidazoles react smoothly to form the relevant cyanoformamides in excellent yields, often within minutes.

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European Journal of Organic Chemistry

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