Solvent-Free Synthesis of Cyanoformamides from Carbamoyl Imidazoles
Date
2017
Authors
Nugent, Jeremy
Campbell, Sarah
VO, Yen Thi-Hoang
Schwartz, Brett
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Publisher
Wiley-VCH Verlag GMBH
Abstract
A straightforward and solvent-free synthesis of various secondary and tertiary cyanoformamides from carbamoyl imidazoles and TMSCN has been developed. Both cyclic and acyclic carbamoyl imidazoles react smoothly to form the relevant cyanoformamides in excellent yields, often within minutes.
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Source
European Journal of Organic Chemistry
Type
Journal article