Widespread expression of γ-glutamyl cyclotransferase suggests it is not a general tumor marker

Amano, Tomonari; Eishi, Yoshinobu; Yamada, Tetsuo; Uchida, Keisuke; Minegishi, Kana; Tamura, Tomoki; Kobayashi, Daisuke; Hiroshi, Kawachi; Suzuki, Takashige; Board, Philip

Widespread expression of γ-glutamyl cyclotransferase suggests it is not a general tumor marker

Date

2012

Authors

Amano, Tomonari

Eishi, Yoshinobu

Yamada, Tetsuo

Uchida, Keisuke

Minegishi, Kana

Tamura, Tomoki

Kobayashi, Daisuke

Hiroshi, Kawachi

Suzuki, Takashige

Board, Philip

Publisher

Histochemical Society

Abstract

γ-Glutamyl cyclotransferase (GGCT) contributes to the γ-glutamyl cycle that regulates glutathione metabolism. Although GGCT has been implicated in several studies as a possible cancer marker, little is known about its distribution in cells and tissues.