Infrared characterization of the Guanine radical cation: finger printing DNA damage

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Authors

Parker, Anthony W
Lin, Ching-Yeh
George, Michael W
Towrie, Michael
Kuimova, Marina K

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American Chemical Society

Abstract

Oxidation of DNA represents a major pathway of genetic mutation. We have applied infrared spectroscopy in 77 K glass with supporting density functional theory (DFT) calculations (EDF1/6-31+G*) to provide an IR signature of the guanine radical cation G+̇,

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Journal of Physical Chemistry B

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Restricted until

2037-12-31