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Multi-purpose functionality for the structural elaboration of the piperazine-2,5-dione motif

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dc.contributor.authorChai, Christina
dc.contributor.authorElix, John
dc.contributor.authorHuleatt, Paul
dc.date.accessioned2015-12-13T22:34:59Z
dc.date.available2015-12-13T22:34:59Z
dc.date.issued2003
dc.date.updated2015-12-11T09:25:09Z
dc.description.abstractMild methods for controlled C- and N-alkylation of 3-benzyloxycarbonylpiperazine-2,5-diones are reported. The benzyloxylcarbonyl substituent can also serve as latent functionality for N-acyliminium ion formation and subsequent trapping enables installation of new carbon and/or heteroatom substituents.
dc.identifier.issn0040-4039
dc.identifier.urihttp://hdl.handle.net/1885/76375
dc.publisherElsevier
dc.sourceTetrahedron Letters
dc.subjectKeywords: 2,5 piperazinedione; piperazine derivative; unclassified drug; alkylation; article; chemical structure Alkylations; Amino acids and derivatives; N-acyliminium ions; Trapping reactions
dc.titleMulti-purpose functionality for the structural elaboration of the piperazine-2,5-dione motif
dc.typeJournal article
local.bibliographicCitation.issue2
local.bibliographicCitation.lastpage265
local.bibliographicCitation.startpage263
local.contributor.affiliationChai, Christina, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationElix, John, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationHuleatt, Paul, College of Physical and Mathematical Sciences, ANU
local.contributor.authoruidChai, Christina, u8615775
local.contributor.authoruidElix, John, u6700470
local.contributor.authoruidHuleatt, Paul, u9804459
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationMigratedxPub5189
local.identifier.citationvolume44
local.identifier.doi10.1016/S0040-4039(02)02571-6
local.identifier.scopusID2-s2.0-0037420990
local.type.statusPublished Version

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