Cofactor promiscuity among F 420 -dependent reductases enables them to catalyse both oxidation and reduction of the same substrate
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Lapalikar, Gauri V
Taylor, Matthew C
Warden, Andrew C
Onagi, Hideki
Hennessy, James E
Mulder, Roger J
Scott, Colin
Brown, Susan E
Russell, Robyn J
Easton, Christopher
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Royal Society of Chemistry
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The recently reported F420H2-dependent reductases (FDRs) catalyse the reduction of aflatoxins and coumarin via hydrogenation of the α,β-unsaturated moiety. We report that three FDRs (MSMEG-2027, MSMEG-6848 and MSMEG-3356) from Mycobacterium smegmatis al
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Catalysis Science and Technology
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2037-12-31
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