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Four-Step Total Synthesis of Selaginpulvilin D

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Date

2017

Authors

Sherburn, Michael
Sowden, Madison

Journal Title

Journal ISSN

Volume Title

Publisher

American Chemical Society

Abstract

An extremely concise total synthesis of a potent phosphodiesterase-4 inhibitory natural product, selaginpulvilin D, is reported. The synthesis features a one-pot, 3-fold electrophilic aromatic substitution sequence to assemble a 9,9-diarylfluorene core. The approach allows access to useful quantities of a selaginpulvilin natural product for the first time.

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Keywords

Citation

URI

http://hdl.handle.net/1885/164502

Collections

ANU Research Publications

Source

Organic Letters

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1021/acs.orglett.6b03793

Restricted until

2037-12-31

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01_Sherburn_Four-Step_Total_Synthesis_of_2017.pdf (585.57 KB)

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