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Yin Yang-1 inhibits tumor cell growth and inhibits p21(WAF1/Cip1) complex formation with Cdk4 and cyclin D1

Date

Authors

Ishii, Hideto

Hulett, Mark

Li, Jian-Mei

Santiago, Fernando

Khachigian, Levon M

Parish, Christopher

Publisher

Spandidos Publications

Abstract

The GLI-Krüppel zinc finger factor yin yang-1 (YY1) is a complex protein that regulates a variety of processes including transcription, proliferation, development and differentiation. YY1 inhibits cell growth in a cell typespecific manner. The role playe

Keywords

Keywords: cyclin D1; cyclin dependent kinase 4; protein p21; transcription factor YY1; animal cell; animal experiment; animal model; animal tissue; article; breast carcinoma; cancer inhibition; carcinoma cell; controlled study; female; glioblastoma; human; human ce Cancer cells; Proliferation; Tumor growth

URI

http://hdl.handle.net/1885/39627

Collections

ANU Research Publications

Source

International Journal of Oncology

Type

Journal article

Access Statement

Open Access

DOI

10.3892/ijo.2012.1362

Downloads

File

Description

01_Ishii_Yin_Yang-1_inhibits_tumor_cell_2012.pdf (775.17 KB)