Yin Yang-1 inhibits tumor cell growth and inhibits p21(WAF1/Cip1) complex formation with Cdk4 and cyclin D1

Date

2012

Authors

Ishii, Hideto
Hulett, Mark
Li, Jian-Mei
Santiago, Fernando
Khachigian, Levon M
Parish, Christopher

Journal Title

Journal ISSN

Volume Title

Publisher

Spandidos Publications

Abstract

The GLI-Krüppel zinc finger factor yin yang-1 (YY1) is a complex protein that regulates a variety of processes including transcription, proliferation, development and differentiation. YY1 inhibits cell growth in a cell typespecific manner. The role playe

Description

Keywords

Keywords: cyclin D1; cyclin dependent kinase 4; protein p21; transcription factor YY1; animal cell; animal experiment; animal model; animal tissue; article; breast carcinoma; cancer inhibition; carcinoma cell; controlled study; female; glioblastoma; human; human ce Cancer cells; Proliferation; Tumor growth

Citation

Source

International Journal of Oncology

Type

Journal article

Book Title

Entity type

Access Statement

Open Access

License Rights

Restricted until