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Synthesis of hexa aza cages, SarAr-NCS and AmBaSar and a study of their metal complexation, conjugation to nanomaterials and proteins for application in radioimaging and therapy

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Date

2013

Authors

Mume, Eskender
Asad, Ali
Di Bartolo, Nadine
Kong, Linggen
Smith, Christopher M
Sargeson, Alan
Price, Roger
Smith, Suzanne

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

A novel hexa aza cage, N1-(4-isothiocyanatobenzyl)-3,6,10,13,16, 19-hexaazabicyclo[6.6.6]icosane-1,8-diamine (SarAr-NCS) was synthesized in good yield and characterized by 1H NMR and electrospray mass spectrometry. A new method for the synthesis of the re

Description

Keywords

Keywords: Electrospray mass spectrometry; Entry point; Immunoreactivities; Lyophilized powders; Metal complexation; PET imaging; Radiolabeling; Silica particles; Amines; Antibodies; Cobalt compounds; Ligands; Silica; Zinc; Copper compounds

Citation

URI

http://hdl.handle.net/1885/62450

Collections

ANU Research Publications

Source

Dalton Transactions

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1039/c3dt51199e

Restricted until

2037-12-31

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Description
01_Mume_Synthesis_of_hexa_aza_cages,_2013.pdf (952.57 KB)

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