A mechanism for Ikaros regulation of human globin geneswitching
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Authors
Keys, Janelle R.
Tallack, Michael R.
Zhan, Ye
Papathanasiou, Panagiotis
Goodnow, Christopher
Gaensler, Karin M
Crossley, Merlin
Dekker, Job
Perkins, Andrew C.
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Blackwell Publishing Ltd
Abstract
The human β globin locus consists of an upstream LCR and functional genes arranged sequentially in the order of their expression during development: 5′-HBE1, HBG2, HBG1, HBD, HBB-3′. Haemoglobin switching entails the successive recruitment of these g
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British Journal of Haematology
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2037-12-31
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