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Epistasis and its possible effects on transmission disequilibrium tests

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Date

2001

Authors

Wilson, Susan

Journal Title

Journal ISSN

Volume Title

Publisher

Cambridge University Press

Abstract

Most approaches to analysing complex genetic disorders are based on an underlying model that assumes that the probability of being affected is mainly due to the effect of a major, single disease locus. Where the penetrance (the conditional probability of

Description

Keywords

Keywords: article; controlled study; covariance; data analysis; disease predisposition; environmental factor; female; gene linkage disequilibrium; gene locus; genetic analysis; genetic disorder; genetic epistasis; genetic model; human; hypothesis; male; methodology

Citation

URI

http://hdl.handle.net/1885/66552

Collections

ANU Research Publications

Source

Annals of Human Genetics

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

Restricted until

2037-12-31

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