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Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease

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Date

2013

Authors

Larter, Claire
Yeh, Matthew
Haigh, W Geoffrey
Van Rooyen, Derrick
Brooling, John
Heydet, Deborah
Nolan, Christopher
Teoh, Narcissus
Farrell, Geoffrey

Journal Title

Journal ISSN

Volume Title

Publisher

Nature Publishing Group

Abstract

Background: Alms1 mutant (foz/foz) mice develop hyperphagic obesity, diabetes, metabolic syndrome, and fatty liver (steatosis). High-fat (HF) feeding converts pathology from bland steatosis to nonalcoholic steatohepatitis (NASH) with fibrosis, which leads

Description

Keywords

Keywords: adenosine triphosphate; alanine aminotransferase; CD36 antigen; cholesterol ester; fatty acid; immunoglobulin enhancer binding protein; triacylglycerol; uncoupling protein 2; adipose tissue; alanine aminotransferase blood level; animal cell; animal experi

Citation

URI

http://hdl.handle.net/1885/77691

Collections

ANU Research Publications

Source

Obesity

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1002/oby.20123

Restricted until

2037-12-31

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01_Larter_Dietary_modification_dampens_2013.pdf (1.93 MB)

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