The total synthesis of (-)-tetrahydrolipstatin
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Bodkin, Jennifer A
Humphries, Edward
McLeod, Malcolm
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CSIRO Publishing
Abstract
Careful control during the bromolactonization of β,γ-unsaturated acid (4) was required to regioselectivity afford the trans-β-lactone (3) as the major diastereomer. Radical debromination of (3) followed by a three-step sequence of reactions afforded th
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Australian Journal of Chemistry
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2037-12-31
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